About Enhancer
| Enhancer ID: | E_00784 |
| Species: | Mus musculus |
| Position : | chr4:115040426-115042426   |
| Year: | 2016 |
| Title: | Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26809507 |
| Cell Source: | HPC-7 |
| CVCL ID: | CVCL_RB19 |
| Experiment Type: | TF-binding/chromatin assay; Chromatin interaction assay; In vivo functional validation |
| High Throughput Method: | ChIP-seq; Hi-C |
| Low Throughput Method: | ChIP-qPCR/ChIP; Transgenic/LacZ assay |
About Target Gene
| Target gene : | Tal1 |
About TF
| TF name : | Max |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Max | C-MYC pathway | pid | 25 |
| Max | Cyclin A:Cdk2-associated events at S phase entry | reactome | 15 |
| Max | Cyclin E associated events during G1/S transition | reactome | 14 |
| Max | Oxidative stress response | panther | 23 |
| Max | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Max | Regulation of Telomerase | pid | 70 |
| Max | Signaling events mediated by HDAC Class I | pid | 89 |
| Max | Validated targets of C-MYC transcriptional activation | pid | 80 |
| Max | Validated targets of C-MYC transcriptional repression | pid | 63 |
| Max | MAPK signaling pathway | kegg | 264 |
| Max | Pathways in cancer | kegg | 321 |
| Max | Small cell lung cancer | kegg | 83 |
| Max | Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 | wikipathways | 122 |
| Max | Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271 | wikipathways | 27 |
| Max | Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900 | wikipathways | 71 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
15 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00775 | chr4:115040426-115042426 | NA | NA | NA |
| E_00776 | chr4:115040426-115042426 | NA | NA | NA |
| E_00777 | chr4:115040426-115042426 | NA | NA | NA |
| E_00778 | chr4:115040426-115042426 | NA | NA | NA |
| E_00779 | chr4:115040426-115042426 | NA | NA | NA |
| E_00780 | chr4:115040426-115042426 | NA | NA | NA |
| E_00781 | chr4:115040426-115042426 | NA | NA | NA |
| E_00782 | chr4:115040426-115042426 | NA | NA | NA |
| E_00783 | chr4:115040426-115042426 | NA | NA | NA |
| E_00785 | chr4:115040426-115042426 | NA | NA | NA |
| E_00786 | chr4:115040426-115042426 | NA | NA | NA |
| E_00787 | chr4:115040426-115042426 | NA | NA | NA |
| E_00788 | chr4:115040426-115042426 | NA | NA | NA |
| E_00789 | chr4:115040426-115042426 | NA | NA | NA |
| E_00790 | chr4:115040426-115042426 | NA | NA | NA |
Expression of Target Genes for the Enhancer