Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00830
Species: Homo sapiens
Position : chr8:128589642-128590670
Year: 2010
Title: 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: prostate cancer
PMID:  20453196
MONDO: MONDO:0008315
Tissue: Prostate
Tissue Ontology ID: UBERON:0002367
Cell Source: LNCaP
CVCL ID: CVCL_0395
Cell Type: prostate carcinoma cell
Cell Ontology ID: CL:0000066
Experiment Type: Enhancer activity assay, Chromatin interaction assay, TF binding assay
High Throughput Method:
Low Throughput Method: ChIP-RT-qPCR, 3C
About Target Gene
Target gene : MYC
About TF
TF name : P300
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 3 found
Enhancer ID Position Tissue Cell Disease
E_00908 chr8:128311200-128667652 Brain medulloblastoma cell medulloblastoma
E_01068 chr8:128540000-128620000 Salivary gland adenoid cystic carcinoma cell salivary gland adenoid cystic carcinoma
E_01069 chr8:128540000-128620000 Prostate gland prostate carcinoma cell prostate cancer
Expression of Target Genes for the Enhancer