Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00839
Species: Homo sapiens
Position : chr3:181708088-181708477
Year: 2012
Title: Sox2 expression in breast tumours and activation in breast cancer stem cells
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: breast carcinoma
PMID:  21822303
MONDO: MONDO:0006120
Tissue: Breast
Tissue Ontology ID: UBERON:0000310
Cell Source: T47D breast carcinoma
CVCL ID: CVCL_0553
Cell Type: breast carcinoma cell
Cell Ontology ID: CL:0000066
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, RT-RT-qPCR, Western blot
About Target Gene
Target gene : SOX2
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00838 chr3:181708088-181708477 Breast breast carcinoma cell breast carcinoma
E_00840 chr3:181708088-181708477 Pluripotent embryonic tissue embryonic stem cell --
Expression of Target Genes for the Enhancer