About Enhancer
| Enhancer ID: | E_00845 |
| Species: | Homo sapiens |
| Position : | chr8:128647663-128667652   |
| Year: | 2016 |
| Title: | Active medulloblastoma enhancers reveal subgroup-specific cellular origins |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | medulloblastoma |
| PMID: | 26814967 |
| MONDO: | MONDO:0005146 |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | MED8A |
| CVCL ID: | |
| Cell Type: | medulloblastoma cell |
| Cell Ontology ID: | CL:0000127 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Transgenic Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | HLX; LHX2; LMX1A |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
8 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00908 | chr8:128311200-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00846 | chr8:128647663-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00847 | chr8:128647663-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00848 | chr8:128647663-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_00380 | chr8:128662857-128663857 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_00381 | chr8:128662857-128663857 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_00805 | chr8:128667652-128669252 | Brain | medulloblastoma cell | medulloblastoma |
| E_00806 | chr8:128667652-128669252 | Brain | medulloblastoma cell | medulloblastoma |
Expression of Target Genes for the Enhancer