About Enhancer
| Enhancer ID: | E_00860 |
| Species: | Homo sapiens |
| Position : | chr17:37648901-37649206   |
| Year: | 2022 |
| Title: | Hnf1b renal expression directed by a distal enhancer responsive to Pax8 |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 36402859 |
| MONDO: | |
| Tissue: | Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | Kidney Tubule Primary Cells |
| CVCL ID: | |
| Cell Type: | kidney tubule epithelial cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | DNase-seq, ChIP-seq, ATAC-seq |
| Low Throughput Method: | qRT-PCR, and ChIP-qPCR |
About Target Gene
| Target gene : | HNF1B |
About TF
| TF name : | PAX8 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| PAX8 | ID | netpath | 38 |
| PAX8 | Pathways in cancer | kegg | 321 |
| PAX8 | Thyroid cancer | kegg | 25 |
| PAX8 | Hs_Thyroid_Stimulating_Hormone_(TSH)_signaling_pathway_WP2032_89823 | wikipathways | 28 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer