About Enhancer
| Enhancer ID: | E_00872 |
| Species: | Homo sapiens |
| Position : | chr4:156635141-156635310   |
| Year: | 2017 |
| Title: | Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 28487391 |
| MONDO: | |
| Tissue: | Whole Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Endothelial cells |
| CVCL ID: | |
| Cell Type: | endothelial cell |
| Cell Ontology ID: | CL:0000115 |
| Experiment Type: | Reporter assay, TF binding, Functional validation |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | qRT-PCR, and ChIP-qPCR |
About Target Gene
| Target gene : | GUCY1A3 |
About TF
| TF name : | ZEB1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| ZEB1 | Integrin-linked kinase signaling | pid | 46 |
| ZEB1 | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer