Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00881
Species: Homo sapiens
Position : chr8:128765000-128767000
Year: 2018
Title: Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: chronic myeloid leukemia
PMID:  29641996
MONDO: MONDO:0011998
Tissue: Bone Marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: K562
CVCL ID: CVCL_0004
Cell Type: chronic myeloid leukemia cell
Cell Ontology ID: CL:0001054
Experiment Type: Chromatin interaction assay, Functional perturbation assay
High Throughput Method: ChIA-PET, RNA-seq
Low Throughput Method: qRT-PCR, and ChIP-qPCR
About Target Gene
Target gene : VEGFA
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 5 found
Enhancer ID Position Tissue Cell Disease
E_00419 chr8:128740000-128790000 Colon colorectal carcinoma cell colorectal carcinoma
E_00595 chr8:128748351-128800823 Pulmonary artery pulmonary artery endothelial cell --
E_00596 chr8:128748351-128800823 Prostate prostate carcinoma cell prostate cancer
E_00167 chr8:128750000-129000000 Breast breast carcinoma cell breast carcinoma
E_00882 chr8:128765000-128767000 Colon colorectal carcinoma cell colorectal carcinoma
Expression of Target Genes for the Enhancer