Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00885
Species: Homo sapiens
Position : chr22:41500000-41501000
Year: 2011
Title: A rearranged EP300 gene in the human B-cell lymphoma cell line RC-K8 encodes a disabled transcriptional co-activator that contributes to cell growth and oncogenicity
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: histiocytic lymphoma
PMID:  21232847
MONDO: MONDO:0004854
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: RC-K8
CVCL ID: CVCL_2148
Cell Type: histiocytic lymphoma cell
Cell Ontology ID: CL:0000576
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: RNA-seq
Low Throughput Method: Luciferase reporter assay, ChIP-RT-qPCR, RT-RT-qPCR, siRNA knockdown
About Target Gene
Target gene : EP300
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer