About Enhancer
| Enhancer ID: | E_00891 |
| Species: | Homo sapiens |
| Position : | chr8:128748243-128748308   |
| Year: | 2022 |
| Title: | A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 36201590 |
| MONDO: | |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Neural stem |
| CVCL ID: | |
| Cell Type: | neural stem cell |
| Cell Ontology ID: | CL:0002672 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | RNA-seq, GAM, 4C-seq |
| Low Throughput Method: | Transgenic Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot, Immunofluorescence |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00419 | chr8:128740000-128790000 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_00112 | chr8:128745000-128752600 | Epithelium | breast epithelial cell | Cancer |
| E_00175 | chr8:128747000-128750000 | Cervical Epithelium | cervical adenocarcinoma cell | cervical cancer |
| E_00646 | chr8:128747000-128753000 | Blood | T lymphoblast | T-cell acute lymphoblastic leukemia |
| E_00945 | chr8:128747680-128753680 | Bone marrow | acute myeloid leukemia cell | acute myeloid leukemia |
Expression of Target Genes for the Enhancer