About Enhancer
| Enhancer ID: | E_00892 |
| Species: | Homo sapiens |
| Position : | chr1:92946000-92958000   |
| Year: | 2022 |
| Title: | GFI1 Cooperates with IKZF1/IKAROS to Activate Gene Expression in T-cell Acute Lymphoblastic Leukemia |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 34980595 |
| MONDO: | |
| Tissue: | Bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | T cell |
| CVCL ID: | |
| Cell Type: | T cell |
| Cell Ontology ID: | CL:0000084 |
| Experiment Type: | TF binding assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | GFI1 |
About TF
| TF name : | IKZF1 |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| IKZF1 | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | pid | 50 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer