Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00902
Species: Mus musculus
Position : chr5:29314881-29315667
Year: 2025
Title: Range extender mediates long-distance enhancer activity.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  40604280
Tissue: limb bud
Tissue Ontology ID: UBERON:0004347
Cell Source: Zone of polarizing activity cells
Cell Type: mesenchymal cell
Cell Ontology ID: CL:0008019
Experiment Type: Enhancer activity assay; Functional perturbation assay
High Throughput Method: ATAC-seq; ChIP-seq; Hi-C; scATAC-seq/scRNA-seq multiome
Low Throughput Method: Luciferase reporter assay; CRISPR knock-in; CRISPR knockout; whole-mount in situ hybridization; skeletal staining; Knock-in mouse
About Target Gene
Target gene : Shh
About TF
TF name : Lhx9
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 4 found
Enhancer ID Position Tissue Cell Disease
E_04542 chr5:29314497-29315862 limb bud embryonic stem cell NA
E_04039 chr5:29314591-29316266 limb bud limb mesenchyme cell NA
E_00900 chr5:29314881-29315667 limb bud mesenchymal cell NA
E_00901 chr5:29314881-29315667 limb bud mesenchymal cell NA
Expression of Target Genes for the Enhancer