Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00915
Species: Homo sapiens
Position : chr14:92450000-92451800
Year: 2014
Title: EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: Ewing sarcoma
PMID:  25453903
MONDO: MONDO:0003368
Tissue: Bone
Tissue Ontology ID: UBERON:0001474
Cell Source: A673 Ewing sarcoma
CVCL ID: CVCL_0080
Cell Type: Ewing sarcoma cell
Cell Ontology ID: CL:0000050
Experiment Type: Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq
Low Throughput Method: RT-RT-qPCR
About Target Gene
Target gene : VRK1
About TF
TF name : EWS-FLI1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer