About Enhancer
| Enhancer ID: | E_00964 |
| Species: | Homo sapiens |
| Position : | chr11:47159000-47159500   |
| Year: | 2014 |
| Title: | Epigenetic Control of SPI1 Gene by CTCF and ISWI ATPase SMARCA5 |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 24498324 |
| MONDO: | |
| Tissue: | Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | HEK293 human embryonic kidney |
| CVCL ID: | CVCL_0045 |
| Cell Type: | embryonic kidney cell |
| Cell Ontology ID: | CL:0002139 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | SPI1 |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer