Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00970
Species: Homo sapiens
Position : chr16:55500100-55502100
Year: 2015
Title: Inhibition of growth, migration and invasion of human bladder cancer cells by antrocin, a sesquiterpene lactone isolated from Antrodia cinnamomea, and its molecular mechanisms
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: acute myeloid leukemia
PMID:  26679052
MONDO: MONDO:0018874
Tissue: Bone Marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: JK1 human erythroleukemia cells
CVCL ID: CVCL_2095
Cell Type: erythroleukemia cell
Cell Ontology ID: CL:0000765
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot
About Target Gene
Target gene : MMP2
About TF
TF name : C-FOS
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_00905 chr16:55499100-55501100 Urinary bladder bladder carcinoma cell bladder carcinoma
E_00971 chr16:55500100-55502100 Bladder bladder carcinoma cell bladder carcinoma
Expression of Target Genes for the Enhancer