Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00975
Species: Homo sapiens
Position : chr5:122453050-122453374
Year: 2023
Title: Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: chronic myeloid leukemia
PMID:  36749647
MONDO: MONDO:0011998
Tissue: Bone Marrow
Tissue Ontology ID: UBERON:0002371
Cell Source: K562
CVCL ID: CVCL_0004
Cell Type: chronic myeloid leukemia cell
Cell Ontology ID: CL:0001054
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, RT-RT-qPCR
About Target Gene
Target gene : PRDM6
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_01089 chr5:122452000-122454500 Adrenal gland neuroblastoma cell neuroblastoma
E_00976 chr5:122453050-122453374 Bronchus bronchial smooth muscle cell --
Expression of Target Genes for the Enhancer