Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_00976
Species: Homo sapiens
Position : chr5:122453050-122453374
Year: 2023
Title: Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  36749647
MONDO:
Tissue: Bronchus
Tissue Ontology ID: UBERON:0002037
Cell Source: Human bronchial smooth muscle cells (HuBrSMCs)
CVCL ID:
Cell Type: bronchial smooth muscle cell
Cell Ontology ID: CL:0000192
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, RT-RT-qPCR
About Target Gene
Target gene : PRDM6
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_01089 chr5:122452000-122454500 Adrenal gland neuroblastoma cell neuroblastoma
E_00975 chr5:122453050-122453374 Bone Marrow chronic myeloid leukemia cell chronic myeloid leukemia
Expression of Target Genes for the Enhancer