About Enhancer
| Enhancer ID: | E_00992 |
| Species: | Homo sapiens |
| Position : | chr4:76192040-76237727   |
| Year: | 2019 |
| Title: | The SNP of rs6854845 suppresses transcription via the DNA looping structure alteration of super-enhancer in colon cells |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | non-small cell lung carcinoma |
| PMID: | 31078271 |
| MONDO: | MONDO:0005233 |
| Tissue: | Lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | NCI-H460 |
| CVCL ID: | CVCL_0459 |
| Cell Type: | non-small cell lung carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay |
| High Throughput Method: | Hi-C |
| Low Throughput Method: | ChIP-RT-qPCR, 3C, RT-RT-qPCR |
About Target Gene
| Target gene : | EREG |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
6 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00620 | chr4:76191350-76202240 | Colon | colon epithelial cell | -- |
| E_00209 | chr4:76192040-76237727 | Inner cell mass | embryonic stem cell | -- |
| E_00213 | chr4:76192040-76237727 | Brain | glioblastoma cell | glioblastoma |
| E_00621 | chr4:76192040-76237727 | Colon | colon epithelial cell | -- |
| E_00607 | chr4:76213678-76224314 | Prostate gland | prostate carcinoma cell | prostate cancer |
| E_00608 | chr4:76213678-76224314 | Colon | colon epithelial cell | -- |
Expression of Target Genes for the Enhancer