Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01056
Species: Homo sapiens
Position : chr12:122510495-122510896
Year: 2023
Title: m6 A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2-mediated IGF1R mRNA stabilization
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  34185427
MONDO:
Tissue: Embryonic Kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: HEK293
CVCL ID: CVCL_0045
Cell Type: embryonic kidney cell
Cell Ontology ID: CL:0002139
Experiment Type: Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method: RNA-seq, ChIP-seq, 3C-seq
Low Throughput Method: CRISPR Knockout, ChIP-RT-qPCR, qRT-PCR, Western blot
About Target Gene
Target gene : SETD1B
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 5 found
Enhancer ID Position Tissue Cell Disease
E_00224 chr12:122510495-122510896 Prostate patient-derived xenograft cell prostate cancer
E_00225 chr12:122510495-122510896 Prostate prostate carcinoma cell prostate cancer
E_00358 chr12:122510495-122510896 Prostate patient-derived xenograft cell prostate cancer
E_00359 chr12:122510495-122510896 Prostate patient-derived xenograft cell prostate cancer
E_01057 chr12:122510495-122510896 Prostate patient-derived xenograft cell prostate cancer
Expression of Target Genes for the Enhancer