About Enhancer
| Enhancer ID: | E_01057 |
| Species: | Homo sapiens |
| Position : | chr12:122510495-122510896   |
| Year: | 2023 |
| Title: | m6 A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2-mediated IGF1R mRNA stabilization |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 34185427 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | P-90 PDX primary |
| CVCL ID: | |
| Cell Type: | patient-derived xenograft cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | RNA-seq, ChIP-seq, 3C-seq |
| Low Throughput Method: | CRISPR Knockout, ChIP-RT-qPCR, qRT-PCR, Western blot |
About Target Gene
| Target gene : | MLXIP |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00224 | chr12:122510495-122510896 | Prostate | patient-derived xenograft cell | prostate cancer |
| E_00225 | chr12:122510495-122510896 | Prostate | prostate carcinoma cell | prostate cancer |
| E_00358 | chr12:122510495-122510896 | Prostate | patient-derived xenograft cell | prostate cancer |
| E_00359 | chr12:122510495-122510896 | Prostate | patient-derived xenograft cell | prostate cancer |
| E_01056 | chr12:122510495-122510896 | Embryonic Kidney | embryonic kidney cell | -- |
Expression of Target Genes for the Enhancer