About Enhancer
| Enhancer ID: | E_01088 |
| Species: | Homo sapiens |
| Position : | chr2:12600000-12649999   |
| Year: | 2020 |
| Title: | Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | neuroblastoma |
| PMID: | 33199677 |
| MONDO: | MONDO:0005070 |
| Tissue: | Adrenal gland |
| Tissue Ontology ID: | UBERON:0002369 |
| Cell Source: | IMR-5/75 |
| CVCL ID: | CVCL_1378 |
| Cell Type: | neuroblastoma cell |
| Cell Ontology ID: | CL:0000031 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, RNA-seq, ATAC-seq, Hi-C |
| Low Throughput Method: | qRT-PCR, and ChIP-qPCR |
About Target Gene
| Target gene : | MYCN |
About TF
| TF name : | PHOX2B; HAND2; GATA3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer