About Enhancer
| Enhancer ID: | E_01089 |
| Species: | Homo sapiens |
| Position : | chr5:122452000-122454500   |
| Year: | 2023 |
| Title: | Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | neuroblastoma |
| PMID: | 36749647 |
| MONDO: | MONDO:0005070 |
| Tissue: | Adrenal gland |
| Tissue Ontology ID: | UBERON:0002369 |
| Cell Source: | CHP-212 |
| CVCL ID: | CVCL_1125 |
| Cell Type: | neuroblastoma cell |
| Cell Ontology ID: | CL:0000031 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq, RNA-seq, ATAC-seq |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | PRDM6 |
About TF
| TF name : | SRF; RBPJ; TEAD1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer