About Enhancer
| Enhancer ID: | E_01089 |
| Species: | Mus musculus |
| Position : | chr3:66845656-66847450   |
| Year: | 2026 |
| Title: | Temporal constraints on enhancer usage shape the regulation of limb gene transcription. |
| Genome Build: | mm39 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 41526337 |
| Tissue: | limb bud |
| Tissue Ontology ID: | UBERON:0004347 |
| Cell Source: | FACS-sorted embryonic limb mesenchymal cells |
| Cell Type: | mesenchymal cell |
| Cell Ontology ID: | CL:0008019 |
| Experiment Type: | Enhancer activity assay; Functional enhancer validation; Chromatin interaction assay; Temporal enhancer profiling |
| High Throughput Method: | H3K27ac ChIP-seq; Capture-HiC; scRNA-seq; RNA-seq; ATAC-seq integration |
| Low Throughput Method: | In vivo LacZ transgenic reporter assay; CRISPR/Cas9 enhancer deletion evidence; Shox2 in situ hybridization; RT-qPCR; fluorescence reporter imaging; flow cytometry |
About Target Gene
| Target gene : | Shox2 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm39)
No overlapping enhancers found in mm39 at this locus.
Expression of Target Genes for the Enhancer