About Enhancer
| Enhancer ID: | E_01091 |
| Species: | Homo sapiens |
| Position : | chr17:44026548-44026648   |
| Year: | 2016 |
| Title: | A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 27149848 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate gland |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | LNCaP |
| CVCL ID: | CVCL_0395 |
| Cell Type: | prostate carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, RT-RT-qPCR |
About Target Gene
| Target gene : | MAPT |
About TF
| TF name : | NFE2L2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFE2L2 | Protein processing in endoplasmic reticulum | kegg | 166 |
| NFE2L2 | Hs_Photodynamic_therapy-induced_unfolded_protein_response_WP3613_89330 | wikipathways | 6 |
| NFE2L2 | Hs_Transcriptional_activation_by_NRF2_WP3_79527 | wikipathways | 6 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer