Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01102
Species: Homo sapiens
Position : chr8:128748315-128750245
Year: 1995
Title: Identification of two enhancer elements downstream of the human c-myc gene
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  7870592
MONDO:
Tissue: Dermis
Tissue Ontology ID: UBERON:0002067
Cell Source: Primary Dermal Lymphatic Endothelial Cells (hLECs)
CVCL ID:
Cell Type: dermal lymphatic endothelial cell
Cell Ontology ID: CL:0002546
Experiment Type: Enhancer activity assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay
About Target Gene
Target gene : MYC
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 10 found
Enhancer ID Position Tissue Cell Disease
E_00419 chr8:128740000-128790000 Colon colorectal carcinoma cell colorectal carcinoma
E_00112 chr8:128745000-128752600 Epithelium breast epithelial cell Cancer
E_00175 chr8:128747000-128750000 Cervical Epithelium cervical adenocarcinoma cell cervical cancer
E_00646 chr8:128747000-128753000 Blood T lymphoblast T-cell acute lymphoblastic leukemia
E_00945 chr8:128747680-128753680 Bone marrow acute myeloid leukemia cell acute myeloid leukemia
E_00595 chr8:128748351-128800823 Pulmonary artery pulmonary artery endothelial cell --
E_00596 chr8:128748351-128800823 Prostate prostate carcinoma cell prostate cancer
E_00636 chr8:128749000-128750000 Esophagus esophageal squamous cell carcinoma cell esophageal squamous cell carcinoma
E_00167 chr8:128750000-129000000 Breast breast carcinoma cell breast carcinoma
E_00651 chr8:128750000-128750100 Colon colorectal carcinoma cell colorectal cancer
Expression of Target Genes for the Enhancer