About Enhancer
| Enhancer ID: | E_01137 |
| Species: | Homo sapiens |
| Position : | chr8:128520000-128551676   |
| Year: | 2016 |
| Title: | Chromatin interactions and candidate genes at ten prostate cancer risk loci |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 26979803 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | DU-145 |
| CVCL ID: | CVCL_0105 |
| Cell Type: | prostate carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Chromatin interaction assay, TF binding assay, Gene expression assay |
| High Throughput Method: | Capture 3C-seq, ChIP-seq, RNA-seq, SNP genotyping array |
| Low Throughput Method: | 3C-qPCR, RT-qPCR |
About Target Gene
| Target gene : | PCAT1 |
About TF
| TF name : | AR; FOXA1; HOXB13; CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
14 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00908 | chr8:128311200-128667652 | Brain | medulloblastoma cell | medulloblastoma |
| E_01135 | chr8:128520000-128551676 | Stomach | esophageal adenocarcinoma cell | esophageal adenocarcinoma |
| E_01136 | chr8:128520000-128551676 | Prostate | prostate carcinoma cell | prostate cancer |
| E_01138 | chr8:128520000-128551676 | Prostate | prostate epithelial cell | -- |
| E_00376 | chr8:128526339-128526710 | Kidney | renal cell carcinoma cell | renal cell carcinoma |
| E_00377 | chr8:128526339-128526710 | Kidney | kidney proximal tubule epithelial cell | -- |
| E_00199 | chr8:128531465-128532665 | Embryonic Kidney | embryonic kidney cell | -- |
| E_00200 | chr8:128531465-128532665 | Skin | melanoma cell | skin melanoma |
| E_00201 | chr8:128531465-128532665 | Skin | melanoma cell | skin melanoma |
| E_00202 | chr8:128531465-128532665 | Umbilical vein | umbilical vein endothelial cell | -- |
| E_00214 | chr8:128531465-128532665 | Brain | glioblastoma cell | glioblastoma |
| E_00246 | chr8:128533830-128534830 | Bone Marrow | T lymphoblast | T-cell acute lymphoblastic leukemia |
| E_01068 | chr8:128540000-128620000 | Salivary gland | adenoid cystic carcinoma cell | salivary gland adenoid cystic carcinoma |
| E_01069 | chr8:128540000-128620000 | Prostate gland | prostate carcinoma cell | prostate cancer |
Expression of Target Genes for the Enhancer