About Enhancer
| Enhancer ID: | E_01155 |
| Species: | Homo sapiens |
| Position : | chr1:1092486-1093650   |
| Year: | 2013 |
| Title: | Identification of an Enhancer That Increases miR-200b~200a~429 Gene Expression in Breast Cancer Cells |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 24086551 |
| MONDO: | MONDO:0006120 |
| Tissue: | Breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | MDA-MB-231 cells |
| CVCL ID: | CVCL_0062 |
| Cell Type: | breast carcinoma cell |
| Cell Ontology ID: | CL:0000646 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Dual-luciferase reporter assay, ChIP-qPCR, RT-qPCR |
About Target Gene
| Target gene : | MIR200B |
About TF
| TF name : | ZEB1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| ZEB1 | Integrin-linked kinase signaling | pid | 46 |
| ZEB1 | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer