About Enhancer
| Enhancer ID: | E_01172 |
| Species: | Homo sapiens |
| Position : | chr17:38022100-38022900   |
| Year: | 2016 |
| Title: | 17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | asthma |
| PMID: | 27848966 |
| MONDO: | MONDO:0004607 |
| Tissue: | Lymphoid tissue |
| Tissue Ontology ID: | UBERON:0001745 |
| Cell Source: | HUT-78 |
| CVCL ID: | CVCL_0337 |
| Cell Type: | T lymphoma cell |
| Cell Ontology ID: | CL:0002419 |
| Experiment Type: | Chromatin interaction assay, Enhancer activity assay, Gene expression assay |
| High Throughput Method: | 4C-seq, ChIP-seq, RNA-seq, DNase-seq |
| Low Throughput Method: | RT-qPCR, Flow cytometry, Cytokine ELISA |
About Target Gene
| Target gene : | ORMDL3 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01171 | chr17:38022100-38022900 | Blood | CD4-positive T cell | asthma |
Expression of Target Genes for the Enhancer