About Enhancer
| Enhancer ID: | E_01174 |
| Species: | Homo sapiens |
| Position : | chr9:22117000-22118500   |
| Year: | 2013 |
| Title: | FOXA1 mediates p16INK4a activation during cellular senescence |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 23443045 |
| MONDO: | |
| Tissue: | Lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | IMR-90 cells |
| CVCL ID: | CVCL_0034 |
| Cell Type: | fetal lung fibroblast |
| Cell Ontology ID: | CL:0000057 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay |
| High Throughput Method: | 3C-seq |
| Low Throughput Method: | Luciferase reporter assay, ChIP-qPCR, EMSA, RT-qPCR, Western blot |
About Target Gene
| Target gene : | CDKN2A |
About TF
| TF name : | FOXA1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOXA1 | AndrogenReceptor | netpath | 167 |
| FOXA1 | Direct p53 effectors | pid | 141 |
| FOXA1 | FOXA1 transcription factor network | pid | 45 |
| FOXA1 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| FOXA1 | Hs_Endoderm_Differentiation_WP2853_88152 | wikipathways | 62 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer