About Enhancer
| Enhancer ID: | E_01222 |
| Species: | Homo sapiens |
| Position : | chr9:21978000-21983000   |
| Year: | 2021 |
| Title: | An interdependent network of functional enhancers regulates transcription and EZH2 loading at the INK4a/ARF locus |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 33761351 |
| MONDO: | |
| Tissue: | Lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | IMR-90 fetal lung fibroblasts |
| CVCL ID: | CVCL_0034 |
| Cell Type: | fetal lung fibroblast |
| Cell Ontology ID: | CL:0000057 |
| Experiment Type: | Functional perturbation assay, Chromatin interaction assay |
| High Throughput Method: | 3C-seq, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, CRISPRi, RT-qPCR, Western blot |
About Target Gene
| Target gene : | CDKN2A |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
7 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01221 | chr9:21973000-21978000 | Lung | fetal lung fibroblast | -- |
| E_00703 | chr9:21980404-21981404 | Brain | neural stem cell | -- |
| E_00704 | chr9:21980404-21981404 | Cervix | cervical adenocarcinoma cell | cervical cancer |
| E_00705 | chr9:21980404-21981404 | Lung | fetal lung fibroblast | -- |
| E_00706 | chr9:21980404-21981404 | Breast | breast carcinoma cell | breast carcinoma |
| E_00707 | chr9:21980404-21981404 | Embryonic Kidney | embryonic kidney cell | -- |
| E_01223 | chr9:21983000-21988000 | Lung | fetal lung fibroblast | -- |
Expression of Target Genes for the Enhancer