Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01230
Species: Homo sapiens
Position : chr17:45414208-45414987
Year: 2020
Title: BCL9/STAT3 regulation of transcriptional enhancer networks promote DCIS progression
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: ductal carcinoma in situ of breast
PMID:  32352029
MONDO: MONDO:0006539
Tissue: Breast
Tissue Ontology ID: UBERON:0000310
Cell Source: DCIS.COM
CVCL ID: CVCL_UE18
Cell Type: breast ductal carcinoma cell
Cell Ontology ID: CL:0000646
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: ChIP-exo, RNA-seq, RPPA
Low Throughput Method: ChIP-qPCR, shRNA Knockdown, RT-qPCR, Western blot, In vivo Invasion Assay
About Target Gene
Target gene : ITGB3
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_01231 chr17:45414208-45414987 Breast mammary epithelial cell --
E_01232 chr17:45414208-45414987 Breast mammary epithelial cell --
Expression of Target Genes for the Enhancer