Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01235
Species: Homo sapiens
Position : chr17:45436112-45436891
Year: 2020
Title: BCL9/STAT3 regulation of transcriptional enhancer networks promote DCIS progression
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  32352029
MONDO:
Tissue: Breast
Tissue Ontology ID: UBERON:0000310
Cell Source: HMEC
CVCL ID: CVCL_U869
Cell Type: mammary epithelial cell
Cell Ontology ID: CL:0002321
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: ChIP-exo, RNA-seq, RPPA
Low Throughput Method: ChIP-qPCR, shRNA Knockdown, RT-qPCR, Western blot, In vivo Invasion Assay
About Target Gene
Target gene : ITGB3
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_01233 chr17:45436112-45436891 Breast breast ductal carcinoma cell ductal carcinoma in situ of breast
E_01234 chr17:45436112-45436891 Breast mammary epithelial cell --
Expression of Target Genes for the Enhancer