Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01251
Species: Homo sapiens
Position : chr14:21993966-21995169
Year: 2024
Title: Comprehensive network modeling approaches unravel dynamic enhancer-promoter interactions across neural differentiation
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  39143563
MONDO:
Tissue: Brain
Tissue Ontology ID: UBERON:0000955
Cell Source: hESC-derived NPCs
CVCL ID:
Cell Type: neural progenitor cell
Cell Ontology ID: CL:0002672
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: RNA-seq, ChIP-seq, ATAC-seq, MPRA
Low Throughput Method: FIMO motif analysis, TF overexpression assay, RT-RT-qPCR, Fisher's exact test, permutation test
About Target Gene
Target gene : CHD8
About TF
TF name : ZNF219; CHD2
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer