Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01270
Species: Mus musculus
Position : chr2:38203254-38204076
Year: 2020
Title: Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies.
Genome Build: mm9
Enhancer Type: Enhancer
Condition: Normal
PMID:  32238901
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: Neuro-2a
CVCL ID: CVCL_0470
Cell Type: neuroblastoma cell
Experiment Type: Enhancer activity assay; In vivo functional perturbation assay; Evolutionary cis-regulatory analysis
High Throughput Method: CAGE; H3K27ac ChIP-seq; H3K4me1 ChIP-seq; DNase-seq; Hi-C
Low Throughput Method: Luciferase reporter assay; PAS1 knockout mouse; PAS1 knock-in mouse; embryonic reporter assay
About Target Gene
Target gene : Lhx2
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm9)
No overlapping enhancers found in mm9 at this locus.
Expression of Target Genes for the Enhancer