About Enhancer
| Enhancer ID: | E_01278 |
| Species: | Homo sapiens |
| Position : | chr2:60495216-60495315   |
| Year: | 2021 |
| Title: | Multiplex CRISPR/Cas9 genome editing in hematopoietic stem cells for fetal hemoglobin reinduction generates chromosomal translocations |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 34853798 |
| MONDO: | |
| Tissue: | Bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | CD34+ hematopoietic stem cells |
| CVCL ID: | |
| Cell Type: | CD34-positive hematopoietic stem cell |
| Cell Ontology ID: | CL:0001029 |
| Experiment Type: | Functional perturbation assay |
| High Throughput Method: | RNA-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, HPLC, Flow cytometry |
About Target Gene
| Target gene : | BCL11A |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer