About Enhancer
| Enhancer ID: | E_01280 |
| Species: | Homo sapiens |
| Position : | chr9:128335472-128336978   |
| Year: | 2020 |
| Title: | Genetic Predisposition to Glioma Mediated by a MAPKAP1 Enhancer Variant |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | glioblastoma |
| PMID: | 31773361 |
| MONDO: | MONDO:0005142 |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | U251 Glioma Cell Line |
| CVCL ID: | CVCL_0021 |
| Cell Type: | glioblastoma cell |
| Cell Ontology ID: | CL:0000127 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, EMSA, ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | MAPKAP1 |
About TF
| TF name : | NFIC |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| NFIC | FOXA1 transcription factor network | pid | 45 |
| NFIC | p75(NTR)-mediated signaling | pid | 74 |
| NFIC | RNA Polymerase III Abortive And Retractive Initiation | reactome | 41 |
| NFIC | RNA Polymerase III Transcription Termination | reactome | 23 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer