About Enhancer
| Enhancer ID: | E_01287 |
| Species: | Homo sapiens |
| Position : | chr2:239866844-239871938   |
| Year: | 2025 |
| Title: | Genomic Locus Tagged by Lung Function GWAS SNV rs12477314 (2q373) Acts as a Regulatory Region for a Systemic Inflammatory Phenotype |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | non-small cell lung carcinoma |
| PMID: | 40512334 |
| MONDO: | MONDO:0005233 |
| Tissue: | Lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | NCI-H460 |
| CVCL ID: | CVCL_0459 |
| Cell Type: | non-small cell lung carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Functional perturbation assay |
| High Throughput Method: | RNA-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, Sanger sequencing |
About Target Gene
| Target gene : | MULTIPLE (CXCL2 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_00990 | chr2:239866844-239871938 | Bladder | bladder epithelial cell | bladder carcinoma |
Expression of Target Genes for the Enhancer