About Enhancer
| Enhancer ID: | E_01290 |
| Species: | Homo sapiens |
| Position : | chr18:64156800-64157000   |
| Year: | 2015 |
| Title: | SATB1 Mediates Long-Range Chromatin Interactions |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | T-cell acute lymphoblastic leukemia |
| PMID: | 26422397 |
| MONDO: | MONDO:0004947 |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Jurkat |
| CVCL ID: | CVCL_0065 |
| Cell Type: | T lymphoblast |
| Cell Ontology ID: | CL:0002419 |
| Experiment Type: | Chromatin interaction, repression validation |
| High Throughput Method: | 3C, ChIP-qPCR, RT-qPCR |
| Low Throughput Method: | qRT-PCR, and ChIP-qPCR |
About Target Gene
| Target gene : | PMAIP1 |
About TF
| TF name : | SATB1 |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| SATB1 | Apoptotic cleavage of cellular proteins | reactome | 18 |
| SATB1 | Caspase Cascade in Apoptosis | pid | 57 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer