Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01294
Species: Mus musculus
Position : chr12:3944001-3947078
Year: 2015
Title: Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  25605944
Cell Source: AtT-20,Pituitary Corticotrope Cell
Experiment Type: TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation
High Throughput Method: ChIP-seq; GRO-seq
Low Throughput Method: CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; 3C; RT-qPCR/qPCR
About Target Gene
Target gene : Pomc
About TF
TF name : NA
About Regulatory State
Regulatory State : Repressed
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_04301 chr12:3944600-3944917 arcuate nucleus of hypothalamus pro-opiomelanocortin neuron obesity
Expression of Target Genes for the Enhancer