About Enhancer
| Enhancer ID: | E_01303 |
| Species: | Mus musculus |
| Position : | chr2:129323600-129328600   |
| Year: | 2024 |
| Title: | Chromatin remodelling drives immune cell-fibroblast communication in heart failure. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | atherosclerosis |
| PMID: | 39443808 |
| MONDO: | MONDO:0005311 |
| Tissue: | heart |
| Tissue Ontology ID: | UBERON:0000948 |
| Cell Source: | Macrophage |
| Cell Type: | macrophage |
| Cell Ontology ID: | CL:0000235 |
| Experiment Type: | Enhancer activity assay; Endogenous enhancer perturbation; In vivo functional validation |
| High Throughput Method: | scATAC-seq |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knockout, RT-RT-qPCR; Mouse genetic deletion/knock-in; In vivo phenotyping |
About Target Gene
| Target gene : | Il1b |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer