About Enhancer
| Enhancer ID: | E_01305 |
| Species: | Mus musculus |
| Position : | chr13:116087428-116088064   |
| Year: | 2024 |
| Title: | A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 39333082 |
| Tissue: | brainstem |
| Tissue Ontology ID: | UBERON:0002298 |
| Cell Source: | Embryonic cranial motor neurons (cMN3/4, cMN6 and cMN7) |
| Cell Type: | motor neuron |
| Cell Ontology ID: | CL:0000100 |
| Experiment Type: | Enhancer activity assay; Single-cell chromatin accessibility profiling; Peak-to-gene linking; Histone modification profiling; Disease-variant functional analysis; In vivo functional validation |
| High Throughput Method: | scATAC-seq; scRNA-seq; scMultiome ATAC + Gene Expression; H3K27ac scCUT&Tag |
| Low Throughput Method: | In vivo transgenic lacZ reporter assay; In vivo phenotyping |
About Target Gene
| Target gene : | Isl1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer