Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01306
Species: Homo sapiens
Position : chr8:128804981-128806980
Year: 2021
Title: ecDNA hubs drive cooperative intermolecular oncogene expression
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: colorectal carcinoma
PMID:  34819668
MONDO: MONDO:0005132
Tissue: Colon
Tissue Ontology ID: UBERON:0001155
Cell Source: COLO320-DM
CVCL ID: CVCL_0219
Cell Type: colorectal carcinoma cell
Cell Ontology ID: CL:0000066
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method: ATAC-seq, ChIP-seq, Hi-C
Low Throughput Method: CRISPRi, Luciferase Reporter Assay, FISH, RT-RT-qPCR
About Target Gene
Target gene : MYC
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 2 found
Enhancer ID Position Tissue Cell Disease
E_01708 chr8:126650000-129950000 Colon colorectal carcinoma cell colorectal carcinoma
E_01295 chr8:128805000-128807000 Colon colorectal carcinoma cell colorectal carcinoma
Expression of Target Genes for the Enhancer