Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01314
Species: Mus musculus
Position : chr1:63189000-63192000
Year: 2019
Title: Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from na?ve pluripotency.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  30990414
Tissue: embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: mouse embryonic stem cells
Cell Type: embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: One of four Zdbf2 regulatory enhancers; duplicated supplied intervals retained as separate experimental-context records; Endogenous enhancer perturbation; In vivo functional validation
High Throughput Method: 4C-seq; chromatin/epigenomic profiling; RNA-seq
Low Throughput Method: Genetic mutant analysis; RT-qPCR; differentiation assays; Mouse genetic deletion/knock-in
About Target Gene
Target gene : Zdbf2
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 3 found
Enhancer ID Position Tissue Cell Disease
E_01240 chr1:63189000-63192000 embryo mouse embryonic stem cell NA
E_01241 chr1:63189000-63192000 embryo mouse embryonic stem cell NA
E_01271 chr1:63189000-63192000 embryonic stem/epiblast cell state embryonic stem cell NA
Expression of Target Genes for the Enhancer