About Enhancer
| Enhancer ID: | E_01318 |
| Species: | Homo sapiens |
| Position : | chr21:43745000-43747000   |
| Year: | 2024 |
| Title: | Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 39316719 |
| MONDO: | MONDO:0006120 |
| Tissue: | Breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | MCF7 |
| CVCL ID: | CVCL_0031 |
| Cell Type: | breast carcinoma cell |
| Cell Ontology ID: | CL:0000646 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, GRO-seq, Hi-C, ChIA-PET, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, 4C-seq, ChIP-RT-qPCR |
About Target Gene
| Target gene : | TFF1 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01370 | chr21:43745000-43747000 | Breast | breast carcinoma cell | breast carcinoma |
Expression of Target Genes for the Enhancer