Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01319
Species: Homo sapiens
Position : chr5:1320000-1322000
Year: 2024
Title: Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  39316719
MONDO:
Tissue: Embryonic Kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: HEK293
CVCL ID: CVCL_0045
Cell Type: embryonic kidney cell
Cell Ontology ID: CL:0002139
Experiment Type: Enhancer activity assay, Functional perturbation assay, TF binding assay, Chromatin interaction assay
High Throughput Method: ChIP-seq, Hi-C, ChIA-PET, RNA-seq, WGS
Low Throughput Method: CRISPR Knockout, RT-RT-qPCR, 4C-seq, ChIP-RT-qPCR, Sanger Sequencing
About Target Gene
Target gene : TERT
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 2 found
Enhancer ID Position Tissue Cell Disease
E_01666 chr5:1230131-1337133 Liver hepatocellular carcinoma cell hepatocellular carcinoma
E_01451 chr5:1320000-1322000 Embryonic Kidney embryonic kidney cell --
Expression of Target Genes for the Enhancer