Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01320
Species: Homo sapiens
Position : chr3:46453226-46459225
Year: 2025
Title: Enhancer transcription profiling reveals an enhancer RNA-driven ferroptosis and new therapeutic opportunities in prostate cancer
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: prostate cancer
PMID:  40082405
MONDO: MONDO:0008315
Tissue: Prostate
Tissue Ontology ID: UBERON:0002367
Cell Source: LNCaP
CVCL ID: CVCL_0395
Cell Type: prostate carcinoma cell
Cell Ontology ID: CL:0000066
Experiment Type: Functional perturbation assay, Enhancer activity assay, Chromatin interaction assay, TF binding assay
High Throughput Method: ATAC-seq, RNA-seq, ChIP-seq, 3C-seq
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot, FISH
About Target Gene
Target gene : LTF
About TF
TF name : HNRNPF; AR
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 3 found
Enhancer ID Position Tissue Cell Disease
E_00186 chr3:46453226-46459225 prostate prostate cancer cell prostate cancer
E_01321 chr3:46453226-46459225 Prostate prostate carcinoma cell prostate cancer
E_01322 chr3:46453226-46459225 Prostate prostate epithelial cell --
Expression of Target Genes for the Enhancer