Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01329
Species: Mus musculus
Position : chr8:121495097-121496097
Year: 2023
Title: Cis interactions in the Irf8 locus regulate stage-dependent enhancer activation.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  36990511
Tissue: blood / hematopoietic system
Tissue Ontology ID: UBERON:0000178
Cell Source: primary dendritic-cell lineage populations
Cell Type: classical dendritic cell
Cell Ontology ID: CL:0000451
Experiment Type: Enhancer essentiality assay; Functional perturbation assay; Chromatin interaction assay
High Throughput Method: RNA-seq; ATAC-seq; ChIP-seq; 4C-seq
Low Throughput Method: CRISPR-Cas9 enhancer deletion; compound-heterozygous enhancer genetics; flow cytometry; RT-qPCR
About Target Gene
Target gene : Irf8
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer