About Enhancer
| Enhancer ID: | E_01338 |
| Species: | Mus musculus |
| Position : | chr12:114461575-114496377   |
| Year: | 2020 |
| Title: | Spt5-mediated enhancer transcription directly couples enhancer activation with physical promoter interaction. |
| Genome Build: | mm10 |
| Enhancer Type: | Super-enhancer |
| Condition: | Normal |
| PMID: | 32251373 |
| Tissue: | spleen |
| Tissue Ontology ID: | UBERON:0002106 |
| Cell Source: | Primary activated mature B cells |
| Cell Type: | mature B cell |
| Cell Ontology ID: | CL:0000785 |
| Experiment Type: | Enhancer activity assay; Chromatin interaction assay; Functional perturbation assay; Endogenous enhancer perturbation |
| High Throughput Method: | ChIP-seq; GRO-seq; ATAC-seq; Hi-C; 3C-seq |
| Low Throughput Method: | CRISPRa; 3C-qPCR; RT-qPCR; ChIP-qPCR |
About Target Gene
| Target gene : | Ighg3 |
About TF
| TF name : | Supt5 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04334 | chr12:114460000-114490000 | blood / hematopoietic system | B cell | Autoimmune Diseases |
| E_01339 | chr12:114461575-114496377 | spleen | mature B cell | NA |
| E_01384 | chr12:114461575-114496377 | spleen | mature B cell | NA |
| E_01374 | chr12:114462800-114464200 | spleen | mature B cell | NA |
| E_01375 | chr12:114465285-114467786 | spleen | mature B cell | NA |
Expression of Target Genes for the Enhancer