About Enhancer
| Enhancer ID: | E_01349 |
| Species: | Homo sapiens |
| Position : | chr10:46073046-46074046   |
| Year: | 2025 |
| Title: | Integrated Omics and Multicohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 40758996 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | C4-2 cells |
| CVCL ID: | CVCL_4784 |
| Cell Type: | prostate carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, RNA-seq, Hi-C |
| Low Throughput Method: | Luciferase reporter assay, ChIP-RT-qPCR, 3C-RT-qPCR, CRISPR knockout, CRISPRi, RT-RT-qPCR |
About Target Gene
| Target gene : | NCOA4 |
About TF
| TF name : | ZNF384 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer