About Enhancer
| Enhancer ID: | E_01367 |
| Species: | Mus musculus |
| Position : | chr8:121088830-121089174   |
| Year: | 2016 |
| Title: | Long-range enhancers modulate Foxf1 transcription in blood vessels of pulmonary vascular network. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 27166834 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | Mouse Embryos |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay; In vivo functional validation |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; 3C; RT-qPCR/qPCR; Transgenic/LacZ assay |
About Target Gene
| Target gene : | Foxf1 |
About TF
| TF name : | Gli3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Gli3 | Ci/Gli processing signaling ( Hedgehog signaling pathway ) | inoh | 17 |
| Gli3 | FAS signaling pathway | panther | 37 |
| Gli3 | Gli processing signaling ( Hedgehog signaling pathway ) | inoh | 15 |
| Gli3 | GLI proteins bind promoters of Hh responsive genes to promote transcription | reactome | 7 |
| Gli3 | GLI3 is processed to GLI3R by the proteasome | reactome | 59 |
| Gli3 | Hedgehog 'off' state | reactome | 43 |
| Gli3 | Hedgehog 'on' state | reactome | 72 |
| Gli3 | Hedgehog | netpath | 39 |
| Gli3 | Hedgehog signaling events mediated by Gli proteins | pid | 49 |
| Gli3 | Hedgehog signaling pathway | panther | 19 |
| Gli3 | Signaling events mediated by the Hedgehog family | pid | 24 |
| Gli3 | Signaling without Hh ( Hedgehog signaling pathway ) | inoh | 7 |
| Gli3 | Hedgehog signaling pathway | kegg | 53 |
| Gli3 | Pathways in cancer | kegg | 321 |
| Gli3 | Basal cell carcinoma | kegg | 51 |
| Gli3 | Hs_Endochondral_Ossification_WP474_87977 | wikipathways | 43 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer