Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01374
Species: Mus musculus
Position : chr12:114462800-114464200
Year: 2020
Title: Spt5-mediated enhancer transcription directly couples enhancer activation with physical promoter interaction.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  32251373
Tissue: spleen
Tissue Ontology ID: UBERON:0002106
Cell Source: mature B
Cell Type: mature B cell
Cell Ontology ID: CL:0000785
Experiment Type: Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay; Endogenous enhancer perturbation
High Throughput Method: ChIP-seq, GRO-seq, ATAC-seq, 3C-seq
Low Throughput Method: 3C-RT-qPCR, ChIP-RT-qPCR, RT-RT-qPCR, CRISPRa; CRISPRa
About Target Gene
Target gene : Ighm
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 4 found
Enhancer ID Position Tissue Cell Disease
E_04334 chr12:114460000-114490000 blood / hematopoietic system B cell Autoimmune Diseases
E_01338 chr12:114461575-114496377 spleen mature B cell NA
E_01339 chr12:114461575-114496377 spleen mature B cell NA
E_01384 chr12:114461575-114496377 spleen mature B cell NA
Expression of Target Genes for the Enhancer